Structured Exercise and Nutritional Guidance in Hispanic/Latino Men with Prostate Cancer: A Pilot Study of SALUD-PC

Cancer Equity; Cancer Detection

Sharon Choi, MD, PhD (UC San Diego)

Humberto Prada, PhD (San Diego State Research Foundation)

Noe Crespo, PhD (San Diego State Research Foundation)

Rana McKay, MD (UC San Diego)

We hypothesize that community-based supervised exercise and nutritional counseling, integrating culturally adapted and patient-directed strategies, will improve physical fitness, metabolic health, and clinical outcomes in Hispanic/Latino (H/L) men with prostate cancer (PCa) undergoing androgen deprivation therapy (ADT). The first aim will evaluate lipidomic changes in H/L men with PCa following initiation of ADT. The second aim will implement a prospective trial that integrates the YMCA Livestrong program with nutrition guidance for H/L men undergoing ADT. Gaining insight into lipidomic alterations in response to ADT may enhance our understanding of the mechanisms driving disparate cardiometabolic outcomes among H/L men. This multimodal lifestyle intervention study focuses on bridging cancer care disparities for H/L men with PCa. The results of this study can be integrated into strategies applied in clinic to enhance physical and metabolic health for H/L men with PCa in our community.