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Evaluation of a Technology Assisted Intervention for Tailoring Oncofertility Care in Female Cancer Survivors: A Pilot Cluster Randomized Controlled Trial

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Pilot Trial: Pediatric Cancers

Pediatric Cancers

H. Irene Su (MCC)

Paula Aristizabal (Rady)

After cancer treatment, female pediatric, adolescent and young adult (AYA) cancer survivors experience more infertility and ovarian failure, which are devastating but preventable outcomes. Young cancer survivors want to know about their reproductive risks and engage in services that reduce risk. Recommended in major clinical guidelines for more than a decade, oncofertility care to discuss individualized reproductive risks and support decision-making about whether to undergo medically effective fertility preservation services remains limited and variable across pediatric and adult cancer care settings.In response to this gap in care, our trans-disciplinary team conducted extensive preliminary work to develop and pilot-test a novel multi-component intervention for oncofertility care that leverages telehealth tools for future scaling up. Intervention components are: 1) electronic health record-based oncofertility needs screen and referral pathway to a virtual oncofertility hub; 2) telehealth oncofertility counseling through the hub; and 3) telehealth oncofertility financial navigation through the hub. The objective of this study is to conduct a pilot trial that will randomize 3 pediatric and 3 adult oncology clinics at UCSD, RCHSD, and City of Hope to intervention or control conditions in order to assess if the intervention increases proportions of newly diagnosed patients who engage in oncofertility care (Aim 1) and improves patient- reported outcomes (Aim 2). This study will yield rigorous pilot data on innovative, scalable telehealth interventions to preserve the reproductive futures of young cancer patients, expand remote delivery of quality oncology care, and bridge silos to provide equitable multi-disciplinary care of oncology patients.

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EXPLORATION

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ACCELERATION

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COLLABORATION

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CURES

Curebound 2022 Concert Featuring Alicia Keyes
Curebound 2022 Concert Featuring Alicia Keyes